A facile and high yielding synthesis of 2,2,3,4,4-d5-androsterone-β-d-glucuronide—an internal standard in dope analysis
✍ Scribed by Peter Gärtner; Clemens Novak; Christian Einzinger; Wolfgang Felzmann; Max Knollmüller; Günter Gmeiner; Wilhelm Schänzer
- Book ID
- 117213557
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 211 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0039-128X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The synthesis of [3,3‐D~2~]4‐hydroxy‐1‐(3‐pyridyl)‐1‐butanone ([3,3‐D~2~]HPB), an internal standard for the analysis of hemoglobin and DNA adducts of tobacco‐specific nitrosamines, is reported. 3‐Pyridine carboxaldehyde was converted to 2‐(3‐pyridyl)‐1, 3‐dithiane. This was condensed wi
The reaction of 2,3:5,6-di-0-isopropylidene-cu-D-mannofuranose with (3methoxycarbonyl-2-oxopropylidene)triphenylphosphorane, catalysed by benzoic acid in dry benzene, gives methyl 4-(2,3:5,6-di-O-isopropylidene-cr-and -@-mannofuranosyl)-3-oxobutanoate in good yield. These compounds are easily transf