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A facile and efficient synthesis of bis(oxazoline)s

✍ Scribed by Wei Jie Li; Sheng Xiang Qiu

Publisher
Journal of Heterocyclic Chemistry
Year
2010
Tongue
English
Weight
91 KB
Volume
47
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

magnified image Thiophene‐2,5‐dicarboxylic acid, benzene‐1,3‐dicarboxylic acid, or furan‐2,5‐di‐carboxylic acid, respectively, reacted with various β‐amino alcohols in toluene under reflux within 24 h, to form nine bis(oxazoline)s (1, 1a, 1b, 1c, 1d, 1e, 2, 2a, 2b, 2c, 3) in good yields through water deprivation via a one‐pot reaction. The synthetic method is facile and efficient and deserves great application potentials in the research and development in the area of bis(oxazoline)s. J. Heterocyclic Chem., (2010).

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