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A Facile Access to 2-CF3-Imidazo[1,2-a]pyridines.

โœ Scribed by Arcady L. Krasovsky; Valentine G. Nenajdenko; Elizabeth S. Balenkova

Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
33
Category
Article
ISSN
0931-7597

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Hydrazonoyl bromides 1a-c react with 5-amino-3phenyl-1H-pyrazole, 5-amino-1H-1,2,4-triazole, 2aminopyridine, 2-aminopyrimidine, and 2-aminobenzimidazole to afford the corresponding imidazo[1,2-b]pyrazoles 10, imidazo[1,2-b]-1,2,4-triazoles 11, imidazo[1,2-a]pyridines 16, imidazo[1,2-a]pyrimidines 17