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A European allele map of the C282Y mutation of hemochromatosis: Celtic versus Viking origin of the mutation?

✍ Scribed by Gérard Lucotte; Florent Dieterlen


Book ID
117726544
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
131 KB
Volume
31
Category
Article
ISSN
1079-9796

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Approximately 85% of patients with typical hereditary hemochromatosis (HH) are homozygous for the C282Y mutation (C282Y/C282Y) in the recently identified candidate gene for HH. However, some HH patients are instead homozygous for the wild-type allele (wt/wt) at this locus. These wt/wt patients may r