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A dynamical study of antibody–antigen encounter reactions

✍ Scribed by Bongini, Lorenzo; Fanelli, Duccio; Piazza, Francesco; De Los Rios, Paolo; Sanner, Michel; Skoglund, Ulf

Book ID
115524738
Publisher
Institute of Physics
Year
2007
Tongue
English
Weight
423 KB
Volume
4
Category
Article
ISSN
1478-3967

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## Abstract Using BIACORE SPR, we have examined the mechanism of temperature effects on the binding kinetics of two closely related antibody Fabs (H10 and H26) which recognize coincident epitopes on hen egg‐white lysozyme (HEL), and whose association and dissociation kinetics are best described by