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A double-blind placebo-controlled trial on the effects of 25

✍ Scribed by Jane Rufford; Andrew Hextall; Linda Cardozo; Vik Khullar

Publisher
Springer
Year
2003
Tongue
English
Weight
180 KB
Volume
14
Category
Article
ISSN
0937-3462

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## Abstract ## Objective To confirm preclinical data suggesting that doxycycline can slow the progression of osteoarthritis (OA). The primary outcome measure was joint space narrowing (JSN) in the medial tibiofemoral compartment. ## Methods In this placebo‐controlled trial, obese women (n = 431)