A double-blind dose-finding study of rol
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E. H. Bennie; S. K. Chakravarti; C. M. B. Jarman; K. Khan; D. Master; G. H. Murr
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Article
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1988
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John Wiley and Sons
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English
โ 460 KB
๐ 2 views
Rolipram improves signal transmission in central noradrenergic neurones with a novel mechanism of action: enhanced noradrenaline (first messenger) synthesis and release, and inhibition of cAMP (second messenger) breakdown. Several comparative trials to prove antidepressant activity are under way. Re