In a double-blind multicentre trial in patients with major depression, the ecacy and the tolerability of sertraline were compared to those of imipramine, during an 8-week acute treatment phase followed by a 16-week continuation treatment phase in treatment responders. A total of 104 patients who met
A double-blind comparative study of sertraline and amitriptyline in outpatients with major depressive episodes
โ Scribed by G. Bersani; V. Rapisarda; N. Ciani; A. Bertolino; G. Sorge
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 442 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0885-6222
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract ## Background The objectives of the study were to compare efficacy and tolerability of venlafaxine ER 75โ150โmg/day with that of citalopram 10โ20โmg/day in elderly patients with major depression according to DSMโIV criteria. ## Methods A randomised, doubleโblind, parallel group 6โmon
Rolipram improves signal transmission in central noradrenergic neurones with a novel mechanism of action: enhanced noradrenaline (first messenger) synthesis and release, and inhibition of cAMP (second messenger) breakdown. Several comparative trials to prove antidepressant activity are under way. Re
The objectives of this study were ยฎrst to compare the responses to moclobemide and sertraline in melancholic and nonmelancholic major depressive patients and secondly to compare the responses of melancholic and nonmelancholic patients in general. Sixty-three patients, with diagnosis of major depress
## Abstract ## Objective Studies indicate that serotoninergic and noradrenergic pathophysiological mechanisms may underlie both alcohol abuse/dependence and depressive disorder. The purpose of this study was to evaluate and compare the effectiveness and tolerability of two serotonergic and noradre
## Abstract ## Objective To assess the efficacy and safety of duloxetine, a serotonin and norepinephrine reuptake inhibitor, in subjects with primary fibromyalgia, with or without current major depressive disorder. ## Methods This study was a randomized, doubleโblind, placeboโcontrolled trial co