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A dose escalation study in sheep of the effects of the benzodiazepine CNS 7056 on sedation, the EEG and the respiratory and cardiovascular systems

โœ Scribed by R N Upton; A M Martinez; C Grant


Book ID
109839025
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
214 KB
Volume
155
Category
Article
ISSN
0007-1188

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The influence of repeated and single administrations of desipramine, amitryptiline, and mianserin on the EEG effects of clonidine has been investigated in rats implanted with chronic cortical electrodes. Clonidine induced a dose-dependent EEG synchronization in control animals. Signs of behavioral d