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A Doctor(s) dilemma: ETV6-ABL1 positive acute lymphoblastic leukaemia

✍ Scribed by Andrea Malone; Stephen Langabeer; Aengus O’Marcaigh; Lorna Storey; Christopher L. Bacon; Owen P. Smith


Book ID
108676912
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
59 KB
Volume
151
Category
Article
ISSN
0007-1048

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## Abstract The __ETV6‐RUNX1__ fusion is the molecular consequence of the t(12;21)(p13;q22) seen in ∼25% of children with acute lymphoblastic leukemia (ALL). Studies have shown that the fusion alone is insufficient for the initiation of leukemia; additional genetic changes are required. Genomic pro