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A DNAzyme That Walks Processively and Autonomously along a One-Dimensional Track

✍ Scribed by Ye Tian; Yu He; Yi Chen; Peng Yin; Chengde Mao

Book ID
101531754
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
355 KB
Volume
117
Category
Article
ISSN
0044-8249

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Herein, we report a DNA nanodevice that autonomously and processively moves along a DNA track. The motion mechanism of this DNA device is reminiscent of that of singleheaded myosins I, a family of cellular protein motors. [1] The DNA device contains a DNA enzyme (DNAzyme) that constantly extracts ch

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A major challenge in nanotechnology is to precisely transport a nanoscale object from one location on a nanostructure to another location along a designated path. The successful construction of self-assembled DNA nanostructures provides a solid structural foundation to meet this challenge. DNA, with