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A DNA replication gene maps near terC in Escherichia coli K12

โœ Scribed by Ben-Neria, Talia ;Ron, Eliora Z.

Publisher
Springer
Year
1991
Tongue
English
Weight
311 KB
Volume
226-226
Category
Article
ISSN
0026-8925

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โœฆ Synopsis

Temperature-sensitive mutants that filamented at the non-permissive temperature were isolated by specific mutagenesis of the terminus region of the Escherichia coli chromosome. Two of them, mapping at about 35 min, failed to divide due to inhibition of DNA replication. Further characterization indicated that these mutants are temperature-sensitive for DNA chain elongation.

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