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A Distinct Regulatory Role of Th17 Cytokines IL-17A and IL-17F in Chemokine Secretion from Lung Microvascular Endothelial Cells

โœ Scribed by Hitomi Fujie; Kaijun Niu; Michiru Ohba; Yoshihisa Tomioka; Haruki Kitazawa; Kengo Nagashima; Takashi Ohrui; Muneo Numasaki


Book ID
113067034
Publisher
Springer
Year
2012
Tongue
English
Weight
493 KB
Volume
35
Category
Article
ISSN
0360-3997

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โ€œAbout 25 years ago, Mosmann & Coffman introduced the TH1 / TH2 paradigm of T helper cell differentiation which helped explain many aspects of adaptive immunity from eliminating intracellular versus extracellular pathogens to induction of different types of tissue inflammation. However, TH1 / TH2 pa