Noninvasive in vivo MRI detection of neu
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G. Vanhoutte; I. Dewachter; P. Borghgraef; F. Van Leuven; A. Van der Linden
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Article
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2005
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John Wiley and Sons
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English
⚖ 255 KB
## Abstract Transgenic mice overexpressing the London mutant of human amyloid precursor protein (APP[V717I]) in neurons develop amyloid plaques in the brain, thus demonstrating the most prominent neuropathological hallmark of Alzheimer's disease. In vivo 3D __T__~2~\*‐weighted MRI on these mice (24