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A direct synthesis of Z-trisubstituted allylic alcohols via the Wittig reaction

✍ Scribed by Sreekumar, C.; Darst, Kevin P.; Still, W. Clark


Book ID
118210244
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
394 KB
Volume
45
Category
Article
ISSN
0022-3263

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2,3]-Wittig rearrangement of 1,1,2-tri¯uoroallylic ethers gave ®ve types of novel 4,4,5-tri¯uoroalk-1,5dien-3-ols. The rearrangement reaction gave the alcohols with perfect (E)\*-selection over the newly created ole®n bond for two substrates. Lipase-catalyzed optical resolution of 4,4,5-tri¯uoroalk-