A direct oxidative route for the synthesis of pyrimidines using heteropolyacids

✍ Scribed by Majid M. Heravi; Samaheh Sadjadi; Hossein A. Oskooie; Rahim Hekmat Shoar; Fatemeh F. Bamoharram

• Publisher: Elsevier Science
• Year: 2009
• Tongue: French
• Weight: 188 KB
• Volume: 50
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.11.105

✦ Synopsis

Pyrimidines are synthesized via a direct oxidative one-pot, three-component, reaction between a 1,3diketone, benzaldehydes and ammonium acetate in the presence of catalytic amounts of Keggin-type heteropolyacids under refluxing conditions in good yields.