A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage
✍ Scribed by Jianwei Wang; Qian Sun; Yohei Morita; Hong Jiang; Alexander Groß; André Lechel; Kai Hildner; Luis Miguel Guachalla; Anne Gompf; Daniel Hartmann; Axel Schambach; Torsten Wuestefeld; Daniel Dauch; Hubert Schrezenmeier; Wolf-Karsten Hofmann; Hiromitsu Nakauchi; Zhenyu Ju; Hans A. Kestler; Lars Zender; K. Lenhard Rudolph
- Book ID
- 116354788
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 936 KB
- Volume
- 148
- Category
- Article
- ISSN
- 0092-8674
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📜 SIMILAR VOLUMES
## Abstract We recently identified a murine hemopoietic stem cell colony which consists of undifferentiated (blast) cells and appears to be more primitive than CFU‐GEMM in the stem cell hierarchy. The progenitors for the colony which we termed “stem cell colony” possess an extensive self‐renewal ca