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A dibenzoylmethane derivative protects H2O2-induced cell death and inhibits lipopolysaccharide-induced NO production in cultured rat astrocytes

✍ Scribed by Takano, Katsura; Sugita, Kumiko; Moriyama, Mitsuaki; Hashida, Koji; Hibino, Satoshi; Choshi, Tominari; Murakami, Rika; Yamada, Masashi; Suzuki, Hiroto; Hori, Osamu; Nakamura, Yoichi


Book ID
123379861
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
71 KB
Volume
68
Category
Article
ISSN
0168-0102

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A dibenzoylmethane derivative protects a
✍ K. Takano; K. Sugita; M. Moriyama; K. Hashida; S. Hibino; T. Choshi; R. Murakami πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 741 KB

Activation of glia has been observed in various neurodegenerative diseases. Excessive production of nitric oxide (NO), as a consequence of increased inducible nitric oxide synthase (iNOS) in glia, contributes to the neurodegeneration. The enhancement of intracellular stresses such as oxidative stres