A Diastereoselective Oxa-Pictet–Spengler-Based Strategy for (+)-Frenolicin B and epi -(+)-Frenolicin B Synthesis

Intra- and Intermolecular Oxa-Pictet–Spe

Intra- and Intermolecular Oxa-Pictet–Spengler Cyclization Strategy for the Enantioselective Synthesis of Deoxy Analogues of (+)-Nanomycin A Methyl Ester, (+)-Eleutherin, (+)-Allo-Eleutherin, and (+)-Thysanone

✍ Rajiv T. Sawant; Satish G. Jadhav; Suresh B. Waghmode 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 229 KB 👁 1 views

## Abstract Enantioselective synthesis of deoxy analogues of pyranonaphthoquinone antibiotics (+)‐nanomycin A methyl ester, (+)‐eleutherin, (+)‐allo‐eleutherin, and (+)‐thysanone was achieved in good overall yield with high enantio‐ and diastereoselectivity from the common intermediate (__R__)‐3‐(2