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A detailed characterization of the adult mouse model of glycogen storage disease Ia

โœ Scribed by Salganik, Susan V; Weinstein, David A; Shupe, Thomas D; Salganik, Max; Pintilie, Dana G; Petersen, Bryon E


Book ID
109885378
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
806 KB
Volume
89
Category
Article
ISSN
0023-6837

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Glycogen storage disease type II (GSDII; Pompe's disease) is an autosomal recessive disease caused by lysosomal -glucosidase deficiency. Skeletal muscle weakness is the most conspicuous clinical symptom of patients suffering from GSDII and skeletal muscle also is prominently involved in the knockout