A dermatoglyphic study of a group of Sicilian children with fragile-X syndrome
β Scribed by Milone, G. ;Conti, L. ;Rizzo, R. ;Sanfilippo, S. ;Sammito, V. ;Romano, C.
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 245 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0148-7299
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In addition to moderate-to-severe mental retardation (MR), the fragile X [fra(X)] mutation produces significant impediments in speech and language. Severe delays in speech and language have been demonstrated in both adult males and young individuals with the fra(X) mutation. Having observed longitud
Fragile X syndrome is associated with the expansion of the number of CGG trinucleotide tandem repeats at the 5Β’ untranslated region of the FMR1 gene. The number of CGG trinucleotide repeats in normal individuals ranges between 5 and 50, in asymptomatic carrier individuals it ranges between 50 and 20
Sleep patterns and endogenous melatonin profiles in 13 fragile X boys between the age of 4.7 and 11.0 years were compared to those of 8 age-matched, normal control boys. Parents recorded sleep patterns on a Sleep Diary Chart for 14 consecutive days. Twelve saliva samples were obtained from 8 fragile