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A demonstration of two-component behaviour of the circular dichroic spectra of poly(L-tyrosine, 3-bromo-L-tyrosine) in trimethylphosphate

✍ Scribed by Jon Applequist; Barbara K. Lunde


Book ID
101716150
Publisher
Wiley (John Wiley & Sons)
Year
1974
Tongue
English
Weight
302 KB
Volume
13
Category
Article
ISSN
0006-3525

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✦ Synopsis


Abstract

The circular dichroic spectrum of poly(Tyr,TyrBr) in trimethylphosphate from 180 to 320 nm is found to be a linear function of composition from 25 to 68% TyrBr, and the spectra of the Tyr and TyrBr components are resolved. For Tyr the resolved spectrum is in agreement with available CD spectra of poly(Tyr). These results are interpreted to mean that the side‐chain conformations of Tyr and TyrBr are not affected by the other component, and that for Tyr the conformation is the same as in poly(Tyr). It is also concluded that poly(Tyr,TyrBr) is helical with the same helix sense as poly(Tyr). The restrictions on the side‐chain conformations are discussed, and it is suggested that the Tyr and TyrBr side chains are all in the same ~χ~1 region.