✦ LIBER ✦

A demonstration of androgen and estrogen receptors in a human breast cancer using a new protamine sulfate assay

✍ Scribed by Marc Lippman; Karen Huff

Publisher: John Wiley and Sons
Year: 1976
Tongue: English
Weight: 514 KB
Volume: 38
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(197608)38:2<868::aid-cncr2820380234>3.0.co;2-z

No coin nor oath required. For personal study only.

✦ Synopsis

Separate receptors for estrogen and androgen are demonstrated in cells from metastic human breast cancer. By criteria of binding affinity, number of binding sites, and specificity of the receptor for different steroids, the receptors are shown to be distinguishable. The protamine sulfate receptor assay technique employed allows both kinds of receptor to be quantified conveniently and reproducibly without interference by plasma steroid-binding components.

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