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A deep intronic mutation in FGB creates a consensus exonic splicing enhancer motif that results in afibrinogenemia caused by aberrant mRNA splicing, which can be corrected in vitro with antisense oligonucleotide treatment

✍ Scribed by Ryan L. Davis; Vivienne M. Homer; Peter M. George; Stephen O. Brennan


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
275 KB
Volume
30
Category
Article
ISSN
1059-7794

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