The metabolism and biliary excretion of i4C-dideoxyinosine (I4C-ddI) has been investigated using the in situ perfused rat liver (PRL) preparation. After 2 h of perfusion through the liver, approximately 7&75 per cent of the total I4C-radiolabel was recovered in the perfusion medium, less than 1 per
A decerebrate, artificially-perfused in situ preparation of rat: Utility for the study of autonomic and nociceptive processing
β Scribed by Anthony E. Pickering; Julian F.R. Paton
- Book ID
- 108186322
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 966 KB
- Volume
- 155
- Category
- Article
- ISSN
- 0165-0270
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Using the in situ perfused rat liver model, the effect of erythromycin (Ery) on the disposition of cyclosporin A (CyA) and the major human metabolite, AMl, was investigated. Prior to perfusion experiments, oral dosing was carried out for three days on three groups of male Sprague-Dawley rats (300-35
We have analysed in briefly anaesthetised rats (1% halothane for 18 minutes) the effects of innocuous and noxious heat, applied to the hindpaw, on evoked c-Fos immunoreactivity at the levels of the parabrachial area (PB), spinal cord, and nucleus of the solitary tract (NTS). After anaesthesia recove