A DEAD box protein facilitates HIV-1 replication as a cellular co-factor of Rev

Purα as a cellular co-factor of Rev/RRE-

Purα as a cellular co-factor of Rev/RRE-mediated expression of HIV-1 intron-containing mRNA

✍ Rafal Kaminski; Nune Darbinian; Bassel E. Sawaya; Dorota Slonina; Shohreh Amini; 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 448 KB

## Abstract To ensure successful replication, HIV‐1 has developed a Rev‐mediated RNA transport system that promotes the export of unspliced genomic RNA from nuclei to cytoplasm. This process requires the Rev responsive element (RRE) that is positioned in the viral transcript encoding Env protein, a