## Abstract We report on a girl with mosaicism (65%) of a de novo supernumerary ring chromosome 7. The main clinical features were delayed psychomotor development, congenital heart defect, facial dysmorphisms, and long hands, fingers, feet and toes. Molecular cytogenetic analysis revealed that the
✦ LIBER ✦
A de novo supernumerary genomic discontinuous ring chromosome 21 in a child with mild intellectual disability
✍ Scribed by Nicoletta Villa; Angela Bentivegna; Adam Ertel; Serena Redaelli; Carla Colombo; Renata Nacinovich; Fiorenza Broggi; Sara Lissoni; Silvia Bungaro; Sankar Addya; Paolo Fortina; Leda Dalprà
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 266 KB
- Volume
- 155
- Category
- Article
- ISSN
- 1552-4825
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## Abstract Neuroligin 1 (__NLGN1__) is one of five members of the neuroligin gene family and may represent a candidate gene for neurological disorders, as members of this family are involved in formation and remodeling of central nervous system synapses. __NLGN1__ is expressed predominantly in the