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A Cyclic AMP Analog, 8-Br-cAMP, Enhances the Induction of Pluripotency in Human Fibroblast Cells

โœ Scribed by Ying Wang; James Adjaye


Book ID
107568195
Publisher
Humana Press Inc
Year
2010
Tongue
English
Weight
870 KB
Volume
7
Category
Article
ISSN
1550-8943

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Induction of cyclic AMP synthesis by for
โœ Nils-Erik Heldin; Ylva Paulsson; Karin Forsberg; Carl-Henrik Heldin; Bengt Weste ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 785 KB

We have studied the effect of increased intracellular levels of cyclic AMP on the growth response to platelet-derived growth factor (PDGF) of human foreskin fibroblasts in culture. It was found that forskolin, a potent stimulator of adenylate cyclase activity, inhibits the stimulatory effect of PDGF