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A CTIVATING R ECEPTORS AND C ORECEPTORS I NVOLVED IN H UMAN N ATURAL K ILLER C ELL -M EDIATED C YTOLYSIS

✍ Scribed by Moretta, Alessandro; Bottino, Cristina; Vitale, Massimo; Pende, Daniela; Cantoni, Claudia; Mingari, Maria Cristina; Biassoni, Roberto; Moretta, Lorenzo

Book ID
118019711
Publisher
Annual Reviews
Year
2001
Tongue
English
Weight
384 KB
Volume
19
Category
Article
ISSN
0732-0582

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A CTIVATING R ECEPTORS AND C ORECEPTORS
A CTIVATING R ECEPTORS AND C ORECEPTORS I NVOLVED IN H UMAN N ATURAL K ILLER C ELL -M EDIATED C YTOLYSIS
✍ Moretta, Alessandro; Bottino, Cristina; Vitale, Massimo; Pende, Daniela; Cantoni 📂 Article 📅 2001 🏛 Annual Reviews 🌐 English ⚖ 384 KB

Natural killer cells can discriminate between normal cells and cells that do not express adequate amounts of major histocompatibility complex (MHC) class I molecules. The discovery, both in mouse and in human, of MHC-specific inhibitory receptors clarified the molecular basis of this important NK ce