A Crystallographic Investigation of Phosphoantigen Binding to Isopentenyl Pyrophosphate/Dimethylallyl Pyrophosphate Isomerase

Influence of naturally-occurring 5′-pyro

Influence of naturally-occurring 5′-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: An X-ray crystallographic study

✍ Daniel E. Holloway; Gayatri B. Chavali; Demetres D. Leonidas; Matthew D. Baker; 📂 Article 📅 2009 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 460 KB 👁 1 views

## Abstract Ribonuclease A is the archetype of a functionally diverse superfamily of vertebrate‐specific ribonucleases. Inhibitors of its action have potential use in the elucidation of the in vivo roles of these enzymes and in the treatment of pathologies associated therewith. Derivatives of adeno