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A critical role for the anterior hippocampus in relational memory: Evidence from an fMRI study comparing associative and item recognition

✍ Scribed by Kelly Sullivan Giovanello; David M. Schnyer; Mieke Verfaellie


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
167 KB
Volume
14
Category
Article
ISSN
1050-9631

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✦ Synopsis


Abstract

Neuroscientific research has established that the hippocampal formation, a structure within the medial temporal lobe (MTL), plays a critical role in memory for facts and events (declarative memory) (Milner et al., 1998). However, its precise role remains unclear. According to one view, the hippocampus has a special role in relating or binding together previously unrelated pieces of information, while another view proposes that the hippocampus is equally involved in all forms of declarative memory, regardless of their demands on relational processing. Using functional magnetic resonance imaging (fMRI), we show that hippocampal activation is modulated by the extent to which a retrieval task depends on relational processing. © 2003 Wiley‐Liss, Inc.