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A critical role for FcgammaRIIB in up-regulation of Fas ligand induced by a microbial polysaccharide

✍ Scribed by M. Piccioni; C. Monari; S. Bevilacqua; S. Perito; F. Bistoni; T. R. Kozel; A. Vecchiarelli

Book ID
108701431
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
887 KB
Volume
165
Category
Article
ISSN
0009-9104

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Background and Objectives: Fas (APO-1) induces apoptosis after binding Fas ligand (FasL). Evidence suggests that tumors may use this interaction to evade the host immune response. Fas/FasL expression has not been reported in esophageal cancer. We hypothesized that Fas expression would render esophag