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A critical role for a tyrosine residue in the cannabinoid receptors for ligand recognition

✍ Scribed by Sean D. McAllister; Qing Tao; Judy Barnett-Norris; Kurt Buehner; Dow P. Hurst; Frank Guarnieri; Patricia H. Reggio; Katharine W. Nowell Harmon; Guy A. Cabral; Mary E. Abood

Book ID: 113993083
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 621 KB
Volume: 63
Category: Article
ISSN: 0006-2952
DOI: 10.1016/s0006-2952(02)01031-6

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## Abstract Hyperphosphorylation at tyrosine is commonly observed in tumor proteomes and, hence, specific phosphoproteins or phosphopeptides could serve as markers useful for cancer diagnostics and therapeutics. The analysis of such targets is, however, a challenging task, because of their commonly