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A Critical Parameter Determining the Aging of DNA–Calcium-Phosphate Precipitates

✍ Scribed by Christian Seelos

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
359 KB
Volume
245
Category
Article
ISSN
0003-2697

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✦ Synopsis

modified the serines residues irreversibly through for-8. Weiss, A. (1993) Cell 73, 209-212. mation of sulfonate esters, resulting in a heterogeneous mixture of molecular weights when analyzed by ESMS. SDS-PAGE alone was unable to detect these slight increases in molecular weight. Because two of the serines modified are found within the tyrosine activation motif sequences, the derivatization of these serines A Critical Parameter Determining the Aging of may therefore affect both the phosphorylation by p56 DNA-Calcium-Phosphate Precipitates lck (6) and the subsequent binding of another T-cell tyrosine kinase, Zap 70 (7, 8). These results therefore indicate that caution should be exercised in the use of Christian Seelos covalent protease inhibitors such as AEBSF and

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