✦ LIBER ✦

A critical look at the TNM classification for laryngeal carcinoma

✍ Scribed by A. B. M. F. Karim; J. H. Kralendonk; K. H. Njo; J. M. Tabak; G. Gort

Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 458 KB
Volume: 65
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19900501)65:9<1918::aid-cncr2820650908>3.0.co;2-b

No coin nor oath required. For personal study only.

✦ Synopsis

A total number of 564 patients with glottic (427) and supraglottic (137) laryngeal carcinoma was prospectively staged clinicoendoscopically (CS) and radiologically (RS). These patients were treated from 1974 to 1985 with quality-controlled high-dose radiation therapy. The validity of CS versus RS was checked in this study with the parameter of recurrence-free adjusted survival (RFADS) at 3 and at 5 years. It appears that RS is more valid and has therapeutic implications in planning the target volume for irradiation. The CS should be regarded as inadequate for radiotherapeutic considerations. The International Union Against Cancer (UICC) 1987 norms for staging laryngeal carcinoma (clinical, endoscopic, and imaging) should be strictly followed.

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