A CRITICAL ANALYSIS OF THE AUTORADIOGRAPHIC DETECTION OF DNA REPAIR IN PRIMARY CULTURES OF RAT HEPATOCYTES
โ Scribed by M. Lonati-Galligani; P. H. M. Lohman; F. Berends
- Book ID
- 118721094
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 151 KB
- Volume
- 407
- Category
- Article
- ISSN
- 0890-6564
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
At present, almost all the information on gene-specific DNA repair in mammals comes from studies with transformed cell lines and proliferating primary cells obtained from rodents and humans. In the present study, we measured the repair of specific DNA regions in primary cultures of nondividing rat h
Previous studies have demonstrated marked differences in the capacity of hepatocytes from rats or hamsters to mediate the metabolic activation of chemical carcinogens to genotoxic (ie, mutagenic) products. Thus far, very few investigations of species differences in DNA repair have been performed. Th