A coupling reaction between tetrahydrofuran and olefins by Rh-catalyzed/Lewis acid-promoted C–H activation
✍ Scribed by Ke Cao; Yi-Jun Jiang; Shu-Yu Zhang; Chun-An Fan; Yong-Qiang Tu; Yuan-Jiang Pan
- Book ID
- 104095430
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- French
- Weight
- 180 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
A novel coupling reaction between tetrahydrofuran and olefins is discovered, in which the consecutive C-C and C-Cl bond-forming process takes place via Rh-catalyzed/lewis acid-promoted C-H activation. This reaction could be developed into a straightforward and effective method for rapid access to 2-(2chloro-2-arylethyl)-tetrahydrofuran compounds.
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