A Convergent Route to the Galbulimima Alkaloids (−)-GB 13 and (+)-GB 16

✍ Scribed by Weiwei Zi; Shouyun Yu; Dawei Ma

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 329 KB
• Volume: 122
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/ange.201002299

✦ Synopsis

alkaloids are a growing family of natural products that were isolated from the bark of Galbulimima belgraveana, which include himbacine (1), (À)-GB 13, (2), [2] himgaline (3), [2] himandrine (4) [2] and (+)-GB 16 (5) (Scheme 1).

Scheme 1. Structures of galbulimima alkaloids and their analogue.

Scheme 2. Retrosynthetic analysis for (À)-GB 13 and (+)-GB 16. Boc = tert-butoxycarbonyl.