A Convergent Route to Geminal Difluorosulfides and to Functionalized Difluorothiochromans, a New Family of Organofluorine Compounds
โ Scribed by Salomon, Pierre; Zard, Samir Z.
- Book ID
- 123618113
- Publisher
- American Chemical Society
- Year
- 2014
- Tongue
- English
- Weight
- 640 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1523-7060
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๐ SIMILAR VOLUMES
Recently we reported on the reactions of cyclic g-diketones and carbethoxycycloalkanones with compound I under basic catalysis. 2 In monoglyme, the products obtained were, invariably a mixture of tautomers arising from protonation of an initially formed 1,6-adduct. In DMSO the products were derivab
The l,&addition of nucleophiles to activated butadienes was first demonstrated by Kohler and Butler (1) in the reaction of sodiomalonic ester with methyl B-vinylacrylate(1).
Consecutive treatment of (trifluoromethoxy)benzene with sec-butyllithium and electrophilic reagents affords previously inaccessible ortho-substituted derivatives in generally excellent yields. 2-(Trifluoromethoxy)phenyllithium acts as the key intermediate. The 3-and 4-isomers can readily be generate