A Convenient Synthetic Route to Polyether-Tagged Cyclam Ligands andTheir Nickel Derivatives

✍ Scribed by Frédéric Bellouard; Françoise Chuburu; Jean-Jaques Yaouanc; Henri Handel; Yves Le Mest

• Book ID: 101281438
• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 272 KB
• Volume: 1999
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/(sici)1099-0690(199912)1999:12<3257::aid-ejoc3257>3.0.co;2-8

✦ Synopsis

A specific strategy is described for the synthesis of stable demonstrated: (i) the low reactivity of PEO derivatives, and (ii) the necessity of a stabiliser arm between the cyclam and polyethylene oxide tagged tetraazamacrocycles (PEOcyclam) in five steps (overall yields for 12 and 13 48% and the PEO chain. Nickel complexes have been prepared and characterised by electrochemistry. 22%, respectively). Various attempts via classical pathways derivatives appeared far from straightforward through a