A convenient synthesis of trifluoromethyl aryl sulfides

✍ Scribed by Béatrice Quiclet-Sire; Radomir N. Saicic; Samir Z. Zard

• Publisher: Elsevier Science
• Year: 1996
• Tongue: French
• Weight: 122 KB
• Volume: 37
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(96)02127-2

✦ Synopsis

Trifluoromethyl aryl sulfides are obtained in moderate/good yields by heating potassium trifluoroacetate and aryl disulfides in sulfolane Copyright © 1996 Elsevier Science Ltd

Trifluoromethyl aryl sulfides are important intermediates in the preparation of biologically active compounds, l dyes, 2 and useful chemical reagents. 3 So far, compounds of this type have been obtained mainly by multi-step procedures involving chlorination of methyl aryl sulfides followed by chloride/fluoride exchange;4, 5 however, o-substituted derivatives cannot be obtained in this way. More direct methods for the