A Convenient Synthesis of Masked β-Ketoaldehydes by the Controlled Addition of Nucleophiles to (Trimethylsilyl)ethynyl Ketones
✍ Scribed by Bromidge, S. M.; Entwistle, D. A.; Goldstein, J.; Orlek, B. S.
- Book ID
- 118169094
- Publisher
- Taylor and Francis Group
- Year
- 1993
- Tongue
- English
- Weight
- 278 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0039-7911
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A variet-y of3-alkynyl perfluoroaikyi ketones were prepared by a trifluoroborane etherate mediated 1,4-addition reaction of ( I -alkynyl)diisopropoxyboranes to a,p-unsaturated ketones substituted by a perfltloroalkyl group. The undesired side reaction, such as 1,2-addition of alkynyl groups, could b