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A convenient synthesis of guanidines from thioureas

โœ Scribed by Maryanoff, Cynthia A.; Stanzione, Robin C.; Plampin, James N.; Mills, John E.


Book ID
111989042
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
426 KB
Volume
51
Category
Article
ISSN
0022-3263

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a b s t r a c t Convenient synthesis of 2-amino-1,5-disubstituted and 2-amino-1,4,5-trisubstituted imidazoles has been reported using readily available starting materials and simple reagents under mild conditions. Guanylation of 1-amidino-3-trityl-thioureas 1 and 7 using mercury(II) chloride (Cautio