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A convenient synthesis of 8-oxoprotoberberine derivatives

✍ Scribed by Somsak Ruchirawat; Werawat Lertwanawatana; Pongtip Thepchumrune


Book ID
104213000
Publisher
Elsevier Science
Year
1980
Tongue
French
Weight
233 KB
Volume
21
Category
Article
ISSN
0040-4039

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✦ Synopsis


The annulation of isoquinoline derivatives to form the 8-oxoprotostep of the reaction involves intra-berbefine molecular derivatives is described. The key alkylation of the Reissert compounds.


πŸ“œ SIMILAR VOLUMES


A convenient synthesis of 5- and 8-nitro
✍ D. Aziane; M. Soukri; A. El Hakmaoui; S. Lazar; M. Akssira; E. M. Essassi; G. Gu πŸ“‚ Article πŸ“… 2002 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 62 KB

## Abstract 3‐Nitrophthalic acid **1** was converted selectively to the two regioisomeric monoesters **2** and **3**, which were subsequently transformed __via__ Curtius rearrangement to the corresponding 5‐ and 8‐nitroquinazoline‐2,4‐diones **4** and **5**, respectively. The reduction of the nitro