Starting fro enolizing 1.2~diketones 1 and (2,2dlathoxyvinylidene)triphenylphosphorane (1) or from 2 and (2.2-dlethoxyvlnyl)triphewlphosphonlu tetrafluorohorate (a) the orthoesters 2 are prepared. 9 can be hydrolyzed under acldlc conditions to glve 5-alkylldene-2(SH)-furan%es lo. Reaction of 1,2-hyd
A convenient synthesis of 2,2-disubstituted 3(2H)-furanones
β Scribed by Drury Caine; William D. Samuels
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- French
- Weight
- 224 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0040-4039
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A simple synthesis of the 3(2H)-furanone ring system is described. The 3(2H)-furanone moeity is a central structural unit in a growing number of natural products including simple compounds such as bullatenone and geiparvarin and more complex compounds such as jatrophone, the eremantholides, and lyc