𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A convenient synthesis of 18-hydroxycorticosterone and 18-hydroxy-11-desoxycorticosterone via stereospecific hypoiodination of 20-hydroxysteroids

✍ Scribed by Ahmed Boudi; Pascale Lemoine; Bernard Viossat; Alain Tomas; Jean Fiet; Hervé Galons


Book ID
104209329
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
350 KB
Volume
55
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

✦ Synopsis


18-Hydroxycorticosterone and 18-hydroxy-1 l-desoxycorticosterone, were obtained via hypoiodination of 20-hydroxy derivatives. The absolute configurations of the C-20 were established by X-ray, only the 20S alcohols reacted under the hypoiodination conditions.