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A convenient synthesis of 1,3-oxazolidin-4-ones and 1,3-oxazin-4-ones

✍ Scribed by Klaus Th. Wanner; Ulrich Weber

No coin nor oath required. For personal study only.

✦ Synopsis

1,3‐Oxazolidin‐4‐ones and 1,3‐oxazin‐4‐ones were synthesized by formal cyclocondensation of imines with α‐ or β‐hydroxy acids.

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## Abstract via acid‐catalyzed acylation of 2‐amino‐tetrahydrochromene‐3‐carboxylates (I)