A convenient synthesis for some new pyrido[3′,2′:4,5]thieno-[3,2-d]pyrimidine derivatives with potential biological activity
✍ Scribed by Carlos Peinador; Vicente Ojea; José Ma. Quintela
- Book ID
- 112130503
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1992
- Tongue
- English
- Weight
- 593 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0022-152X
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📜 SIMILAR VOLUMES
A ready one-pot preparation for pyridothienopyrimidines hearing various suhstituents at position 2 of the pyrimidine ring is reported. The aza Wittig-type reaction of iminophosphoranes derived from the aldehyde 4 with heterocumulenes leads to functionalized fused pyrimidines. Iminophosphoranes 6, 2-
## Abstract magnified image The carbodiimides **5**, obtained from reactions of iminophosphorane **4** with aromatic isocyanates, reacted with amines, phenols or ROH to give 2‐substituted 5,6,7,8‐tetrahydropyrido[4′,3′:4,5]thieno[2,3‐__d__]‐pyrimidin‐4(3__H__)‐one 7 in the presence of catalytic am