## Abstract For Abstract see ChemInform Abstract in Full Text.
A convenient stereoselective synthesis of fluorinated α-alkylidene-γ-butyrolactone derivatives
✍ Scribed by Xiyan Lu; Zhong Wang; Jianguo Ji
- Book ID
- 104215618
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 296 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0040-4039
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Stereoselective Synthesis of (Z)-α-Alkylidene-γ-butyrolactone from 2-Alkyn-1-one. -Reduction of the recently reported (Z)-3-iodo-3-alken-1ones (I) with sodium borohydride gives the corresponding alkenols (II) without loss of stereochemistry. These undergo a Pd(0)-catalyzed cyclization with CO to for