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A convenient regioselective synthesis of pyrano[3,2-b]acridones involving nucleophilic addition to benzyne

✍ Scribed by Mónika Rudas; Miklós Nyerges; László Tőke; Béla Pete; Paul W. Groundwater

Book ID
104262206
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
186 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

Acridone 8 was prepared by the nucleophilic addition of aniline 4 to benzyne 5. Hydrolysis of the ester group, followed by cyclisation gave the acridone 8, which was subsequently converted to the pyrano[3,2-b]acridin-4-ones 11 and 17.

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